Post by Deleted on Feb 21, 2012 2:28:33 GMT -5
So a reply in another thread started me on an internet quest which revealed some interesting information that started my mind to pondering.
Something often repeated (and I am guilty of it too) is that ferrets are said to imprint upon their food at an early age. I think this is a poor term - imprint - it may well be that in fact they are simply ADDICTED to the foods forced upon them! This may be why some ferrets make the switch and others simply cannot - their own bodies may be chemically addicted to the food that is slowly killing them!
Keep in mind that ferrets are often used as models for MANY human systems and health issues. Mice too, get used for this. so of course one has to wonder if scientific discoveries work in the other direction?
In another thread about strange edible things ferrets show a strong attraction to I commented about recently reading an article that science had proved eating french fries produces the same effects on the brain as does cannabis (marijuana)!
Looking into this further I discovered several links and this one looks very interesting to say the least:
www.ncbi.nlm.nih.gov/pubmed/20445053 with the abstract quoted below in case the link is inactive: (I bolded what could be relevant for ferrets - the rest is a lot of scientific mumbo jumbo) for the more curious among us keep doing more searches using "endocannabinoid ferret", "endocannabinoid system" etc and follow the multiple links that show up in pubmed. Its an interesting trip!
In real people terms the endocannabinoid system is a system that looks for and receives specific compounds that eventually release dopamine ( or happy happy joy joy hormones) in the brain as well as tell the brain to keep eating or if its hungry. What's interedting too once you start looking into this system is that it isn't tied to JUST the brain - it ties in to the pancreas, insulin, adipose tissue (fat) as well as stress regulators of the body!
can you say WOW! Can you see the light? Ferrets, although obligate carnivores DO have an attraction to sugars and sweets and what is a consistent ingredient in kibbles? Sugars - whether simple or complex - they are there! And I propose they do one thing for the ferret.... get it and keep it addicted to kibble!
Abstract
The endocannabinoid (eCB) system plays central roles in the regulation of food intake and energy expenditure. Its alteration in activity contributes to the development and maintenance of obesity. Stimulation of the cannabinoid receptor type 1 (CB(1) receptor) increases feeding, enhances reward aspects of eating, and promotes lipogenesis, whereas its blockade decreases appetite, sustains weight loss, increases insulin sensitivity, and alleviates dysregulation of lipid metabolism. The hypothesis has been put forward that the eCB system is overactive in obesity. Hippocampal circuits are not directly involved in the neuronal control of food intake and appetite, but they play important roles in hedonic aspects of eating. We investigated the possibility whether or not diet-induced obesity (DIO) alters the functioning of the hippocampal eCB system. We found that levels of the two eCBs, 2-arachidonoyl glycerol (2-AG) and anandamide, were increased in the hippocampus from DIO mice, with a concomitant increase of the 2-AG synthesizing enzyme diacylglycerol lipase-alpha and increased CB(1) receptor immunoreactivity in CA1 and CA3 regions, whereas CB(1) receptor agonist-induced [(35)S]GTPgammaS binding was unchanged. eCB-mediated synaptic plasticity was changed in the CA1 region, as depolarization-induced suppression of inhibition and long-term depression of inhibitory synapses were enhanced. Functionality of CB(1) receptors in GABAergic neurons was furthermore revealed, as mice specifically lacking CB(1) receptors on this neuronal population were partly resistant to DIO. Our results show that DIO-induced changes in the eCB system affect not only tissues directly involved in the metabolic regulation but also brain regions mediating hedonic aspects of eating and influencing cognitive processes.
So if you read this far, you may be definitely intrigued by what ferrets get served! So when we convert a ferret in reality we are performing an intervention! Going at their change in diet as if we are moving them away from an addiction - may shed new light on how to approach a transition and how to KEEP them on the right track and the importance of not letting them fall back into an addicted state!
Seeing their introduction to processed foods as a forced addiction also sheds new light on the shameful practices of many breeders - does it not?
Cheers,
Kim
Something often repeated (and I am guilty of it too) is that ferrets are said to imprint upon their food at an early age. I think this is a poor term - imprint - it may well be that in fact they are simply ADDICTED to the foods forced upon them! This may be why some ferrets make the switch and others simply cannot - their own bodies may be chemically addicted to the food that is slowly killing them!
Keep in mind that ferrets are often used as models for MANY human systems and health issues. Mice too, get used for this. so of course one has to wonder if scientific discoveries work in the other direction?
In another thread about strange edible things ferrets show a strong attraction to I commented about recently reading an article that science had proved eating french fries produces the same effects on the brain as does cannabis (marijuana)!
Looking into this further I discovered several links and this one looks very interesting to say the least:
www.ncbi.nlm.nih.gov/pubmed/20445053 with the abstract quoted below in case the link is inactive: (I bolded what could be relevant for ferrets - the rest is a lot of scientific mumbo jumbo) for the more curious among us keep doing more searches using "endocannabinoid ferret", "endocannabinoid system" etc and follow the multiple links that show up in pubmed. Its an interesting trip!
In real people terms the endocannabinoid system is a system that looks for and receives specific compounds that eventually release dopamine ( or happy happy joy joy hormones) in the brain as well as tell the brain to keep eating or if its hungry. What's interedting too once you start looking into this system is that it isn't tied to JUST the brain - it ties in to the pancreas, insulin, adipose tissue (fat) as well as stress regulators of the body!
can you say WOW! Can you see the light? Ferrets, although obligate carnivores DO have an attraction to sugars and sweets and what is a consistent ingredient in kibbles? Sugars - whether simple or complex - they are there! And I propose they do one thing for the ferret.... get it and keep it addicted to kibble!
Abstract
The endocannabinoid (eCB) system plays central roles in the regulation of food intake and energy expenditure. Its alteration in activity contributes to the development and maintenance of obesity. Stimulation of the cannabinoid receptor type 1 (CB(1) receptor) increases feeding, enhances reward aspects of eating, and promotes lipogenesis, whereas its blockade decreases appetite, sustains weight loss, increases insulin sensitivity, and alleviates dysregulation of lipid metabolism. The hypothesis has been put forward that the eCB system is overactive in obesity. Hippocampal circuits are not directly involved in the neuronal control of food intake and appetite, but they play important roles in hedonic aspects of eating. We investigated the possibility whether or not diet-induced obesity (DIO) alters the functioning of the hippocampal eCB system. We found that levels of the two eCBs, 2-arachidonoyl glycerol (2-AG) and anandamide, were increased in the hippocampus from DIO mice, with a concomitant increase of the 2-AG synthesizing enzyme diacylglycerol lipase-alpha and increased CB(1) receptor immunoreactivity in CA1 and CA3 regions, whereas CB(1) receptor agonist-induced [(35)S]GTPgammaS binding was unchanged. eCB-mediated synaptic plasticity was changed in the CA1 region, as depolarization-induced suppression of inhibition and long-term depression of inhibitory synapses were enhanced. Functionality of CB(1) receptors in GABAergic neurons was furthermore revealed, as mice specifically lacking CB(1) receptors on this neuronal population were partly resistant to DIO. Our results show that DIO-induced changes in the eCB system affect not only tissues directly involved in the metabolic regulation but also brain regions mediating hedonic aspects of eating and influencing cognitive processes.
So if you read this far, you may be definitely intrigued by what ferrets get served! So when we convert a ferret in reality we are performing an intervention! Going at their change in diet as if we are moving them away from an addiction - may shed new light on how to approach a transition and how to KEEP them on the right track and the importance of not letting them fall back into an addicted state!
Seeing their introduction to processed foods as a forced addiction also sheds new light on the shameful practices of many breeders - does it not?
Cheers,
Kim