|
Post by Deleted on Feb 25, 2014 0:26:39 GMT -5
I feel awful! Somehow my ferrets got the lid off some ibuprofen while I was at work! I know for a fact they got into it at least 6 hours ago. Now my little boy Rowdy is lethargic and retching!! I got some activated charcoal and he lapped it happily (with Ferretone). But after reading this article: www.aspcapro.org/sites/pro/files/b-veccs_jan01.pdf I am very afraid I am too late!! It's almost midnight and there is no ferret vet open! Is there anything else I can do? He's sleeping now, he won't wake up for more than a few minutes before finding somewhere to sleep. I'm so so so so worried and I feel awful!! If anything happens to him I'll never forgive myself, cause I was home for a few moments earlier in the day and had I caught it I could have administered Charcoal so much sooner. [img src="http://i1105.photobucket.com/albums/h352/JW_2012/Emoticons/T_T.png" src="http://i1105.photobucket.com/albums/h352/JW_2012/Emoticons/ .png" style="max-width:100%;"]
|
|
|
Post by Deleted on Feb 25, 2014 0:35:15 GMT -5
And he will still wakes up easily, he just tries to go back to sleep again if there's not anything really interesting like a treat.
|
|
|
Post by Deleted on Feb 25, 2014 0:58:03 GMT -5
Yaaaay! He just got up and gave me a decent sized piddle! Sorry for all the updates, I'm just feeling very frantic and powerless and every little thing is a victory.
Also, his eyes were nice and bright and open instead of squinty and dull.
|
|
|
Post by Deleted on Feb 25, 2014 1:43:56 GMT -5
I can't really give any help but just wanted you to know others are here for you and that I will be praying for your babies!
|
|
|
Post by katt on Feb 25, 2014 2:30:50 GMT -5
Do you have Facebook? Find me: Katt Crouch I have some articles I can send you. Or PM me your email.
|
|
|
Post by katt on Feb 25, 2014 2:34:01 GMT -5
No matter how he is acting tonight, he needs to go to the vet ASAP in the morning. Symptoms of ibuprofen toxicity in ferrets typically develop between 4-8 hours after ingestion - but can start to show as late as 48 hours after, so just because he is okay now or in the am does NOT mean he is in the clear.
|
|
|
Post by katt on Feb 25, 2014 2:37:29 GMT -5
"Activated charcoal adsorbs ibuprofen and can be given via a stomach tube or a dosing syringe at a dose of 1-2 g/kg.2,16 Activated charcoal should be repeated, since ibuprofen undergoes enterohepatic recirculation.2 A cathartic, such as sorbitol, should be used in combination with activated charcoal unless the ferret is dehydrated or has diarrhea.16"
"The approach to the diagnosis and treatment of renal disease in ferrets is the same as for other companion animal species.17 Diuresis for 24-36 hours is recommended to prevent acute renal failure."
"The approach to the diagnosis and treatment of renal disease in ferrets is the same as for other companion animal species.17 Diuresis for 24-36 hours is recommended to prevent acute renal failure. The placement of a 22-24 gauge peripheral catheter in the lateral saphenous, the cephalic, or the jugular vein may be necessary for parenteral fluids.13,18 When this is not an option, an intraosseous catheter can be placed in the tibial crest (preferably), humerus, or femur using a 20- 22 gauge, 1.5 inch spinal needle.13,18 Catheter placement is performed with the ferret under anesthesia. Isoflurane using an induction chamber or a face mask provides the safest means of anesthesia in the ferret.13,19 An infusion pump should be used to prevent overhydration, and the ferret should be monitored for wet lung sounds or the development of a heart murmur, which could indicate overhydration.13 The ferret’s BUN, creatinine, urine specific gravity and hepatic enzymes should be monitored closely. However, the serum creatinine level alone may not accurately reflect the presence of renal failure in ferrets. Baseline values and repeated values checked at 36, 48, 72 hours post-exposure are recommended. Urine output should be evaluated, and the ferret should be monitored for acidosis and electrolyte shifts. Hyperphosphatemia, hypocalcemia and reduced total carbon dioxide can be seen in ferrets with renal disease.17 The prognosis for ferrets with acute renal failure depends on laboratory findings and response to therapy. Clinical signs of renal disease in ferrets may include depression, lethargy, inappetence, weight loss, oral ulcers, polyuria and polydipsia, melena, rear leg weakness, and dehydration.13 The development of papillary necrosis is generally considered an irreversible condition.a,7,10 The ferret should be placed on gastrointestinal protectants for 5-7 days post-exposure to prevent gastric ulceration. Misoprostol is a synthetic prostaglandin (PGE1) that inhibits gastric acid and has a cytoprotective effect on gastric mucosa.21 Misoprostol has been used to treat GI ulceration in dogs secondary to ibuprofen ingestion and could be used in ferrets at a dose of 1-5 micrograms/kg PO q 8h.26 Sucralfate at a dose of 1/8 gram q 6 h is commonly used to treat and prevent gastric ulceration in ferrets.14,22 Sucralfate can bind to ulcers and erosions and protect them from further exposure to gastric acid, bile acids, and pepsin.21 In addition, sucralfate is considered to be cytoprotective through stimulation of prostaglandin production.22,23 H2 receptor antagonists have been recommended for the treatment of ibuprofen-induced gastric irritation and ulceration in dogs and cats.7 Cimetidine (5-10 mg/kg PO, SC, IM, or IV, q 8 h) or famotidine (0.25-0.5 mg/kg PO, IV, q 24 h) could be given to the ferret in addition to sucralfate therapy.b 20,14 Metoclopramide (0.2 - 1 mg/kg q 6-8 h PO, SC) can be used to control vom-iting"
"in ferrets. The animal should be monitored for clinical signs suggestive of gastritis which may include weight loss, vomiting, hypersalivation, and bruxism. Ancillary Treatment: With ibuprofen ingestion, ancillary measures, such as nutritional support, are necessary for complete recovery of the ferret. Anorectic ferrets are at risk of developing hepatic lipidosis and hypoglycemia and should be hospitalized for fluid therapy and parenteral treatment. A pharyngostomy tube may be necessary to provide adequate nutrition. The technique is identical to that described for cats and utilizes an 8-10 French pediatric feeding tube.13 Adult ferrets can be forcefed liquid soy-based or meat-based diets at 2-5 ml, 3 - 4 times daily.13,17 The resting energy requirement for ferrets is 70 kcal/ day.13 A more complete diet should be used if forced feeding continues for more than one day.15 Diazepam at 1 mg/kg IM or less could be given to stimulate appetite.14 Possible Drug Interactions Substances that could cause an interaction with ibuprofen include coumarin-type anticoagulants, which could increase the risk of gastrointestinal bleeding. Glucocorticoids may also increase the likelihood of GI ulcerations.5,21 Other NSAIDS, such as salicylates, phenylbutazone, and indomethacin, could potentiate the gastrointestinal effects of ibuprofen.1 It is unknown what affects other NSAIDs would have on the CNS effects of ibuprofen in ferrets."
Ibuprofen Ingestion in Ferrets: 43 Cases January 1995-March 2000) Jill A. Richardson, DVM; Rachel A. Balabuszko, CVT
|
|
|
Post by katt on Feb 25, 2014 2:52:37 GMT -5
I just want to emphasize how dangerous this can be. Even a dog or cat vet can help. Please get to the vet, any vet, as soon as humanely possible! Please keep us posted.
|
|
|
Post by Deleted on Feb 25, 2014 2:57:24 GMT -5
Please call emergency vets around your area. Even though they may not specialize in ferrets, most can treat as a kitten and keep him stable until you can get him to your vet in the morning. We have a list of vets (https://docs.google.com/a/fiu.edu/file/d/0B0bVtK9isoVJalJVN3NneEVhRFk/edit?usp=sharing) feel free to see if we have any ferret vets on that list near you. Check the sites as well as some have emergency clinic numbers.
|
|
|
Post by katt on Feb 25, 2014 3:03:44 GMT -5
|
|
|
Post by Deleted on Feb 25, 2014 8:14:49 GMT -5
Thank you everyone! He is acting much better this morning, bright eyed, curious, and he just went to the potty and gave me another piddle! It it really early here but we are packing up the crate and will be at the vets when they open in about 30 minutes, the ferret vet actually, woohoo.
Here's hoping he's out of the woods.
I will let you guys know what happens when I get back. Thank you for all of your prayers!!
|
|
|
Post by miamiferret2 on Feb 25, 2014 9:24:34 GMT -5
Need to take him to vet bc kidney probs show no signs until far advanced. Take no chances with this.
|
|
|
Post by Sherry on Feb 25, 2014 9:27:42 GMT -5
He made it through the night, that's excellent! And please, yes- let us know what the vet says
|
|
|
Post by Deleted on Feb 25, 2014 11:28:01 GMT -5
You guys will be in my thoughts.
|
|
|
Post by Deleted on Feb 25, 2014 11:35:30 GMT -5
OK! We're back from the vet! Prognosis is good! But he is not out of the woods yet.
We went in and they did bloodwork and his levels (including kidney function) were all normal except he was a little dehydrated (cause he hasn't felt like drinking). But he wasn't showing any signs of anemia from GI Bleeding or reduced kidney function, yay!
He got Sub Q fluids and I will be giving him more tonight, tomorrow morning, and tomorrow night just to be sure. He also got Sucralfate and more charcoal and we have Sucralfate to give him .2 mls every 8 hours.
Then we're going back Thursday for more bloodwork.
Overall I am breathing a sigh of relief but will be watching him like a hawk.
Poor baby doesn't feel good, his tummy hurts, he's nauseous, and the vet poked him with a needle 3 times and gave him nasty medicine. Poor baby. But he's home and sleeping.
Off to work!
Thank you for everyone who prayed and sent good thoughts, here's hoping the worst is past!!
Laurel
|
|