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Post by miamiferret2 on Jan 16, 2014 8:48:05 GMT -5
8.5 yrs old and adrenal. tumors get to point where they no longer respond to treatment. As disease progresses interval time between implants shortens and many find they need to re implant every 6 months.
Add in a melatonin implant every four months
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Post by miamiferret2 on Jan 16, 2014 12:41:30 GMT -5
Dr. Gandolfi is pretty much one of the experts on using deslorelin for prevention of ACD. you are in good hands. if he has not seen this before, I'd take his word for it. he was one of the vets that I harassed for information back in the fall of 2010 when i was thinking about implanting Sonny. he was a kit at that time.
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Post by Deleted on Jan 16, 2014 13:49:51 GMT -5
8.5 yrs old and adrenal. tumors get to point where they no longer respond to treatment. As disease progresses interval time between implants shortens and many find they need to re implant every 6 months. Add in a melatonin implant every four months Tnx for the advice and remark. Ram is 8,5 but was diagnosed with adrenal in June 2012. and has implant since. His earlier regular 6 months apart checkups (UZV, urine/stool-microbiology and parasitology, complete bloodscreen - biochem/hematology) haven't presented anything except insulinoma which is controlled with methylpred since September 2011. msav, I haven't noticed wheter you mentioned, are your ferrets descented? anal glands issues can trigger agression and restlessness. And did your vet do regular blood hormone levels check-up in order to determine implant efficiency or were you replacing it based only on clinical signs?
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Post by msav on Jan 16, 2014 14:27:06 GMT -5
sorry I am in USA nearly all mill ferrets are sold descented and fixed.
This was for prevention of Adrenal. so they did not do hormone level test. They were 8 month old when they were first implanted. They have never had there hormone levels checked
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Post by Deleted on Jan 16, 2014 15:43:53 GMT -5
I understand. Here, all ferrets are sold unfixed, unvaccinated, undescented and most of them unsocialized. Like we're on diff planets.  Maybe hormone levels check up wouldn't be bad idea if it can be done.
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Post by miamiferret2 on Jan 16, 2014 16:28:02 GMT -5
msav what they do is that right before they implant the young ferret, they will run a Tenn panel to see what their baseline (normal) levels are. then every year they will test to see whether any changes.
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Post by miamiferret2 on Jan 16, 2014 16:31:20 GMT -5
Petra i speak only of early neutered ferrets which is what is most common here in america. all ferrets sold by commercial breeders are neutered at a very young age which is why we have a bigger problem with early adrenal here in the states. i actually know absolutely nothing about intact ferrets. I have never owned one. i would assume that there is no point in implanting them at under 6 months since a) they are not in danger of developing adrenal and b) they don't go into season until after 6 months right? I have no idea.
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Post by Deleted on Jan 16, 2014 16:54:48 GMT -5
I figured, miamiferret In fact, there were cases in Croatia when female ferrets went into season as early as 4-5 months. For instance, our lates' Baltazar's mom Seven of Nine was born on 23.1.2005. and she gave birth to Baltazar and 6 of his siblings on 19.7.2005. Her sister Moogie which was our fourth ferret, haven't. I suppose daylight and warmth had great influence on this. As for the genetic predisposition for adrenal under the age of 1, I shall dig through my books some more regarding this topic. We have only one ferret which is neutered and descented very young (Zhou, stray ferret rescued last November, origin: Marshall - by tats, Italy - by location where he was found) and he is completely different than our other ferrets who were castrated at age od 8-9 months and are non-decented. He looks a bit underdeveloped compared to other ones, he's very lovable and non-confrontational in interaction with other ferrets. He has adrenal and just got his first implant in late December, 2013. It seems, with implant or not, he completely lacks agression. The only signs of adrenal were severe hair loss, ichy flaky skin and drinking own urine.
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Post by miamiferret2 on Jan 1, 2016 15:20:00 GMT -5
update: as some here know, i began implanting my Marshall Farms early neuter, Sonny, with the deslorelin implant when he was 5 months old. this was done for preventive purposes. Sonny's implant was done every year in January. We live in the U.S.
Sadly, our Sonny passed away at 5 years and 4 months due to unrelated heart issues. Necropsy was performed and the left adrenal gland was normal. right adrenal gland had a small cyst which pathologist and veterinarian advised was not a tumor. however, the cysts are often the pre-cursor to tumors. I still consider this to be a good result. He was not adrenal. He was not showing signs of it and he had the most beautiful coat for an early neuter Marshall Farms that was over 5 years old. his coat was amazing. many early neuter MF ferrets have adrenal lesions or tumors at an early age.
Obviously, my ferret is only one. more data is needed. i hope that more ferret owners will be willing to take the plunge and use the deslorelin (starting at a young age) for prevention or to delay the onset of ACD and that they share their results with others. This is how we learn and because of the sharing of info over the years, ferret owners and their veterinarians are now able to do many things to help our pets live better lives.
We currently have a new baby named Vito and I do intend to proceed with the use of the Deslorelin on him. However, I will be adding in melatonin implants as recommended by Dr. Jerry Murray. Hopefully, Vito will have good results as well.
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Post by Heather on Jan 1, 2016 15:32:25 GMT -5
Thank you for coming in and updating us on your results. I have been following Sonny since you got him and I have to admit some curiosity as to how well the DES worked for him. I'm sorry that he developed a heart condition but he lived a wonderful and full life with you. I will be interested to watch your newest little one, Vito grow and make much trouble  ciao
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Post by msav on Jan 2, 2016 11:21:14 GMT -5
Hmm. this has got me thinking. I probably should have had this done when Koufos passed. I still have Cassia she is going on 8 years. She has thinning hair but it is thin all over (not Bald) and not just thin in one particular spot. She still comes out and explores everyday but only for about 40 mins. When she goes I would definitely be interested in if she developed any Adrenal tumors. This would help me with the decision to continue the yearly implant preventative treatment on the rest of my ferrets. Koufos and Cassia were my first that were started on des at 8 months and have had their continued yearly treatment every December. (was 2 months past last year due to the shortage)
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Post by Thérèse on Jan 2, 2016 11:30:58 GMT -5
Condolences on Sonny's passing. He was such a character
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Post by Sherry on Jan 2, 2016 12:20:58 GMT -5
Thanks for updating us on his necropsy Xio. And it is really good to hear a positive result on the des as a preventative.
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